Alzheimer's and Stem Cell Research

When Ronald Reagan was dying of Alzheimer'swould be Parkinson's disease.
disease, Nancy Reagan became interested in stemHowever Parkinson's disease affects only a small and
cell research and its potential for treating Alzheimer'sspecialized population of brain cells. Other uses for
disease.stem cell therapy might be Type-1 Diabetes, which is
As a result, there has been a continuing growingcaused by the loss of discrete insulin-producing cells in
voice of supporters on this issue.the pancreas.
Ronald Reagan's death from Alzheimer's diseaseThe most promising use for stem cell therapy could
increased the support for human embryonic stem cellbe for spinal cord injuries in which a few crucial nerve
research. This research requires the destruction ofcells die, such as the injury that paralyzed actor
human embryos.Christopher Reeve. But in the case of Alzheimer's,
Many supporters of stem cell research believe thatthe requirement for the recreation of brain cells is
the transplants of show great potential for curingtoo complex.
certain diseases such as Parkinson's and diabetes.However, promising this research might sound for
Medical researchers believe that someday, embryoAlzheimer's, the medical community views the results
cell studies may lead to insights into Alzheimer's.of an Alzheimer's cure from stem cell therapy as a
Most proponents of stem cell research felt that if"fairy tale"
nothing else, stem cells bearing the genetic hallmarks"To start with, people need a fairy tale," said Ronald
of Alzheimer's might help scientists assess theD.G. McKay, a stem cell researcher at the National
potential usefulness of new drugs. But few scientistInstitute of Neurological Disorders and Stroke. "Maybe
feel there is a direct benefit for Alzheimer's fromthat's unfair, but they need a story line that's
stem cell therapy.relatively simple to understand." Other researchers
The overall consensus of scientist and researchers isconsider it disingenuous to talk about Alzheimer's in
that stem cell transplant therapy does not sound likeconnection with stem cell research.
a viable treatment for Alzheimer's. There is anStem cell experts admit that there are diseases that
obvious lack of genuine enthusiasm surrounding stemmay one day be cured by embryonic stem cell
cell therapy as having any practical potential to treattreatments, but these expert state that Alzheimer's
Alzheimer's.is among the least likely disease to benefit from this
The basis of the stem cell research focuses ontherapy.
human embryonic stem cells that can cloneI think the chance of doing repairs to Alzheimer's
themselves into any kind of tissue. This amazingbrains by putting in stem cells is small," said stem cell
ability of these cells have led scientists to believe thatresearcher Michael Shelanski, co-director of the Taub
these stem cells could be a "universal patch" toInstitute for Research on Alzheimer's disease and the
replace any injured or non-functioning organ.Aging Brain at the Columbia University Medical Center
"Some studies have suggested, for example, thatin New York, echoing many other experts. "I
stem cells injected into an injured heart can spur thepersonally think we're going to get other therapies
development of healthy new heart muscle. Amongfor Alzheimer's a lot sooner.
the more promising targets of such "cellular therapies"