| The true causes of Alzheimers disease
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| | Alzheimers disease.
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| remain elusive. However, researchers have
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| | The plaque deposits are sticky patches in
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| made progress in understanding the
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| | the brain which contain beta amyloid
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| neurological roots of this debilitating
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| | protein. Plaque blocks communication
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| condition.
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| | pathways between neurons, which results
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| The disease is named after Alois
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| | in the memory problems and learning
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| Alzheimer, who was the first to identify
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| | inabilities associated with Alzheimers
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| the peculiar plaques and tangles in the
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| | disease.
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| brain, which is characteristic of the
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| | The degree of cognitive impairment
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| illness. Till the final decades of the
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| | depends on the amount of plaque present.
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| twentieth century, Alzheimers could be
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| | Plaque acts by interfering with the
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| diagnosed accurately only by a
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| | normal functioning of acetylcholine,
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| post-mortem examination.
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| | which helps to transmit nerve messages.
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| Nowadays, scientists are beginning to
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| | Treatment for Alzheimers disease involves
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| uncover precisely what is happening and
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| | using acetylcholinesterase inhibitors,
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| why those characteristic tangles and
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| | which works by blocking enzymes that
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| plaques crop up in the brain.
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| | consume the acetylcholine. This
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| Many of the symptoms of Alzheimers
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| | medication is effective during the early
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| disease are caused by neurofibrillary
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| | stages of the disease before too much
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| tangles in the brain. Microscopic
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| | plaque has already built up.
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| filaments clog the neurons. These
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| | Some research seems to indicate that
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| filaments are made up of an abnormal kind
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| | plaques cause tangles. One study took
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| of Tau protein.
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| | proteins from mice to eliminate the
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| In a normal brain, Tau protein bonds into
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| | plaque-causing beta amyloid. They found
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| microtubules and enables transmission of
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| | that the proteins got rid of the tangles
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| messages from one neuron to another. But
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| | as well. Similar effects have been
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| in an Alzheimer brain, instead of bonding
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| | brought about by other medications as
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| into message pathways, Tau protein bonds
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| | well.
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| with itself. And the neuron messages go
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| | Others believe that both plaques and
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| nowhere.
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| | tangles are the result of other
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| Since the neurons are clogged, signals
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| | processes. One possible culprit is
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| from the environment are no longer
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| | swollen axons. Axons are critical for
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| transmitted the way they should be. That
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| | transmitting messages between neurons.
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| is why severe cognitive impairment is one
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| | When axons swell, they may block message
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| of the symptoms of Alzheimers disease.
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| | transmission and perhaps lead to the
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| Scientists speculate that Tau protein
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| | plaques and tangles which bring on
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| malfunction which results in
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| | Alzheimers disease.
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| neurofibrillary tangles is caused by beta
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| | Scientists are working hard at uncovering
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| amyloid protein, but this is yet to be
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| | the causes of Alzheimers disease, which
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| conclusively proved.
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| | may sooner or later lead to a
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| It is beta amyloid protein that causes
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| | comprehensive cure for this dreaded
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| plaques between neurons, which is the
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| | condition.
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| other main damage to the brain in
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